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Several countries, including the United Kingdom, have introduced maternal pertussis vaccination during pregnancy to protect infants from infection following national increases in pertussis notifications.
The objective of this study was to estimate the effectiveness of maternal pertussis vaccination in protecting infants against laboratory-confirmed pertussis infection.
Mothers of 10 cases (17%) and 39 controls (71%) received pertussis vaccine in pregnancy.
This gave an unadjusted VE of 91% (95% confidence interval [CI], 77%–97%). Several countries have observed recent increases in pertussis cases, including England and Wales , the United States , Portugal  and New Zealand .
These increases have occurred despite sustained periods of high reported vaccine coverage.